In summary, the cytokines and chemokines released in response to adenovirus infection are pro-inflammatory in nature and include cytokines IL-1α, IL-1β, IL-6, IL-8, IFN-γ, IFN-α, and TNF-α and chemokines CCL2, CCL3, and CXCL10. This evidence concerns the gene CXCL8 and adenoviridae infectious disease.