In addition, the Ag85b/ESAT6/CFP10-specific IFN-γ cell immune response and the ESAT6-specific IL-2 cell immune response induced by AEC/BC02 in the Mtb latent infection mice were both higher than those in normal mice, while Ag85b/CFP10-specific IL-2 cell immunity was lower than that in normal mice. Here, IL2 is linked to disease arising from reactivation of latent virus.