Among 1943 DEGs, 11 DEGs (CDK1, EGFR, FYN, UBC, MYC, CCNB1, FOS, RHOB, CDC6, CDC20, and CHEK1) were reported as the hub-DEGs/proteins that may play the key roles in NSCLC progression. This evidence concerns the gene CCNB1 and non-small cell lung carcinoma.