GPT and chronic hepatitis B virus infection: However, HBV-related complications and deaths, mainly caused by LC and HCC, may be contained if chronic HBV-infected subjects can be treated appropriately when they pass through the stage of chronic hepatitis B (CHB) that is characterized by the presence of HBsAg and HBV DNA in the blood with variable levels of liver damage, shown by the elevation of alanine aminotransferase (ALT) in the blood [4,5].