Therefore, our results suggest that the A-b and UB-010 fractions can also induce apoptosis and the T-f, A-f, A-b, and UB-010 fractions trigger differentiation through the NFkB alternative pathway and could be considered for further testing as an anti-NFkB agent in colon cancer treatment. Here, NFKB1 is linked to malignant colon neoplasm.