The KLK14-ABP (but not the KLK2-or KLK3-ABP) inhibited the migration of LNCaP cells engineered to express KLK14 indicating that KLK14 is required for tumor cell migration, a key step in the process of metastasis but also that ABPs can be used as inhibitors to delineate the biological role(s) of the targeted proteases [37]. This evidence concerns the gene KLK14 and neoplasm.