There are also studies on the expression profile of all ABC transporter genes; in 2013, the genes ABCA5/6/8/9/10, ABCB1/5/11, ABCC6/9, ABCD2/4, ABCG5, and ABCG8 were shown to be significantly downregulated, and the genes ABCA2/3/7/12, ABCB2/3/8/9/10, ABCC1/4/5/10/11/12, ABCD1/3, ABCE1, ABCF1/2/3, and ABCG1 were shown to be upregulated in post-treatment tumours compared with non-neoplastic tissues. This evidence concerns the gene ABCG2 and neoplasm.