Relaxin signaling, cAMP signaling, morphine addiction, GnRH signaling, calcium signaling, endocrine resistance, inflammatory mediator modulation of TRP channels, estrogen signaling, proteoglycans in cancer, pertussis, retrograde endocannabinoid signaling, and adrenergic signaling in cardiomyocytes are all examples of signaling pathways. Here, GNRH1 is linked to cancer.