TGFB1 and infection: GLPG-0187 targets the integrins αvβ1, αvβ3, αvβ5, αvβ6, α5β1, and αvβ8, which, in addition to allowing infection of the virus, may play a potential role in SARS-CoV-2 pathogenesis by mediating activation of TGF-β, angiogenesis, lung injury, and inflammation [8,36].