BACE1 and Alzheimer disease: The top three fruit extracts based on overall strong inhibitory activities were selected for further investigation of phenolic profiles by liquid chromatography–electrospray ionization–tandem mass spectrometry (LC-ESI-MS/MS), neurotoxicity, and neuroprotective effects using a neuronal-like PC-12 cell model and an in vivo Drosophila model of AD (co-expression of human APP and BACE-1).