MMP9 and cancer: Simvastatin and rosuvastatin reduced MMP2 and MMP9 (p < 0.01) expression in lung cancer tissue samples collected from 12 patients undergoing surgery; MMPs concentration is regulated by NFκB and its expression is also reduced by statins in normal lung tissue, whereas action on MMPs only occurred in cancer tissue [21] (Figure 2) (Table 5 and Table 6).