APOE and atherosclerosis: Moreover, V55 treatment enhanced Socs3 and Dab2 expression (inhibitors of cytokine signaling and NF-κB pathway), Apoe (associated to atherosclerosis control), Igf1 (encoder a protein with analogous effects to insulin) and Fgf10 (fibroblasts growth factor) (p < 0.05), see Figure 3.