AIH mice show a lower aspartate aminotransferase (AST) and alanine aminotransferase (ALT) level in serum after treatment with 100 or 200 mg/kg BBR and have a reduced TNF-α, IFN-γ, IL-1β, and IL-2 mRNA and protein expression in serum. This evidence concerns the gene IL1B and autoimmune hepatitis.