Disturbances of the gut microbiota may worsen signs of Alzheimer’s disease by activating signalling pathways such as the TLR4/NF-κB, ROS/JNK and NF-κB/BACE1 pathways; inhibiting these pathways with anthocyanins was suggested to decrease neuroinflammation and Alzheimer’s pathology [175]. The gene discussed is NFKB1; the disease is Alzheimer disease.