Furthermore, treatment with NK151, NK173, NK175, or their (3:1:1) mix suppressed IS-induced colitis: they suppressed colonic IL-1β and IL-6 expression and the NF-κB+CD11c+ cell number along with the fecal endotoxin level, meanwhile increasing the IL-10 cytokine level in the colon. This evidence concerns the gene IL1B and colitis.