LEP and obesity due to melanocortin 4 receptor deficiency: Third, there were many other significant metabolic factors associated with mTG and macrosomia, such as interleukin-17, leptin, and adiponectin, as well as other key issues caused by maternal overweight/obesity and the imbalance of lipid metabolism, such as non-alcoholic fatty liver disease in children later in life, which requires more in-depth studies.