Differential diagnosis of AVB must include medications (especially antiarrhythmic and neuroactive drugs), ischemic etiologies (anterior and inferior myocardial infarction), degenerative diseases (e.g., Lev–Lenègre syndrome), cardiomyopathies (such as cardiomyopathy induced by lamin A/C mutations), other infections (such as endocarditis with perivalvular abscesses, Chagas disease), infiltrative processes (sarcoidosis, amyloidosis), and metabolic and neuromuscular disorders (myotonic dystrophy, Emery–Dreyfuss, and limb-girdle muscular dystrophies) [37]. Here, LMNA is linked to cardiomyopathy.