IL1B and COVID-19: In both severe COVID-19 and MIS-C, suppression of the overactive immune response with corticosteroids has become standard care [63], although MIS-C often also requires the neutralization of autoantibodies with intravenous immunoglobulin or specific antagonists to IL-1 (anakinra) or IL-6 (tocilizumab—although its use is no longer recommended) [64,65,66].