NLRP3 and Sepsis: In vivo, geniposide activated AMPKα to inhibit the accumulation of myocardial reactive oxygen species (ROS) in a mouse model of LPS-induced sepsis-induced myocardial dysfunction, thereby blocking the apoptosis and pyroptosis of myocardial cells mediated by NOD-like receptor protein 3(NLRP3), and ameliorating sepsis-induced myocardial dysfunction [60].