In CCl4-intoxicated rats with liver fibrosis, RA (10 mg/kg) could reduce the fibrosis grade, ameliorate biochemical indicators (albumin, globulin, alanine aminotransferase, glutamate-pyruvate transaminase) and histopathological morphology, and downregulate the liver TGF-β1 and CTGF expression [269]. Here, GPT is linked to Hepatic fibrosis.