Little is known about the effect of raspberries on granulocyte-macrophage colony-stimulating factor (GM-CSF), except that quercetin, a bioflavonoid component of raspberry, stimulated the production of GM-CSF and the recruitment of dendritic cells to human prostate cancer PC-3 cells following classical endoplasmic reticulum (ER)/Golgi pathways, thus enabling host immunosurveillance [310] and considering a novel approach to avoid the significant toxicity associated with the IFN and IL-2 based immunotherapy [311]. This evidence concerns the gene CSF2 and Familial prostate cancer.