Cymbopogon flexuosus oil and copaiba (Copaifera officinalis) resin oleo showed low toxicity in the test, while copaiba essential oil and geranium (Pelargonium × ssp) essential oil showed high toxicity and a greater inhibition of acetylcholinesterase, indicating a potential bioactivity for neurodegenerative diseases. The gene discussed is ACHE; the disease is neurodegenerative disease.