In the multivariate analysis, GGT levels (OR: 1.022; 95% CI: 1.008–1.036; p = 0.0021) and the G/G genotype of the SNP rs738409 in PNPLA3 (OR: 13.2; 95% CI: 2.2–77.5; p = 0.0040) were associated with cirrhosis. The gene discussed is PNPLA3; the disease is Cirrhosis.