Alzheimer’s disease (AD) is associated with a degeneration of hippocampal and cortical neurons due to the overproduction of cytotoxic β-amyloid (Aβ) peptides followed by an extracellular formation of plaques and intracellular deposition of hyperphosphorylated tau (τ) protein-forming neurofibrillary tangles (NFTs) [1,2]. Here, MAPT is linked to Alzheimer disease.