To investigate the effect of reversible inhibition of CPT1, we used a well-established Drosophila model for Huntington’s disease [11] (Q128HD-FL) in which the human HTT complementary DNA (cDNA) with 128 glutamine repeats is expressed in all neuronal tissues (genotype: elav-Gal4/+; UAS-hFLHD-128Q/+;). Here, LGALS4 is linked to juvenile Huntington disease.