Genetic alterations, including the mutation of the epidermal growth factor receptor, or v-Ki-ras2 kirsten rat sarcoma viral oncogene homolog, and the fusion of anaplastic lymphoma kinase (ALK), RET proto-oncogene (RET), or v-ros UR2 sarcoma virus oncogene homolog 1 (ROS1), occur in non-small cell lung cancers [44]. The gene discussed is ALK; the disease is non-small cell lung carcinoma.