The XO level was detected as 13.65 U/L in the control group, 16.08 U/L in the hyperuricemia group, 7.5 U/L in the allopurinol group, 4.88 U/L in the MJM60662 group, and 3.11 U/L in the MJM60396 group (Figure 3D). The gene discussed is XDH; the disease is hyperuricemia.