HTRA1 and age-related macular degeneration: On the other hand, interesting results were reported by the CATT trial (Comparison of AMD Treatments Trials) including patients from 43 centers, who were tested for the presence of SNP rs1061170 in the CFH gene and rs2230199 in the C3 gene in addition to rs10490924 (ARMS2) and rs11200638 (HTRA1).