SIRT1 and periodontitis: The analysis showed that the SIRT1 rs3818292 AA genotype was less frequent in the periodontitis group than in the control group (78.1% vs. 89.4%, p = 0.001), while the AG genotype was more frequent in patients over 60 years old than in the control group (20.5% vs. 10.6%, p = 0.003).