In addition, the SIRT1 rs7895833 AA genotype was less frequent in the periodontitis group than in the control group (60.0% vs. 75.2%, p = 0.007), while the AG genotype was more frequent in the periodontitis group than in the control group (37.6% vs. 23.6% p = 0.012). This evidence concerns the gene SIRT1 and periodontitis.