In the work of Hou et al., the AA genotype of rs7895833 was associated with a significantly decreased risk of CRS1 (OR = 0.49), whereas in our study, the genotype AA was less frequent in the periodontitis patients’ group, in comparison to the control group (60.0% vs. 75.2%, p = 0.007) in the male population. The gene discussed is TWIST1; the disease is periodontitis.