Tumors with EGFL7-positive cancer cells (n = 9) were less infiltrated with (IE)CD4+ and (IE)CD8+ lymphocytes compared to negative ones (n = 50) (median 1.67, range 0.33–12.33 vs. median 6.00, range 0.67–26.33, p = 0.022 and median 5.00 range 1.0 to 12.67 vs. 13.17 range 1 to 53, p = 0.04, respectively). Here, EGFL7 is linked to cancer.