APOB and metabolic syndrome: While HDL particles serve as the preferential CE donor (TG acceptor) for CETP-mediated exchange [53,54], TGRLs and their remnants that are elevated in atherogenic dyslipidemia also undergo CETP-mediated exchange in which they are the CE acceptor (TG donor) with other apoB particles, including LDL (this is “homotypic exchange,” as opposed to “heterotypic exchange” between apoA-I- and apoB-containing particles), resulting in TG-enriched LDL [35,55].