Other than γδT cells and CCL20, a common concept of psoriatic march believes that the release of excessive proinflammatory cytokines such as TNF-α and IL-1 in psoriasis causes chronic low-grade systemic inflammation, leading to insulin resistance, visceral adiposity, hypertension and dyslipidemia, and, finally, the development of type 2 diabetes and cardiovascular disease [85]. The gene discussed is CCL20; the disease is hypertensive disorder.