For example, T helper 17 cells, which produce IL-17, are proven to be involved in the pathogenesis of multiple autoimmune diseases, such as systemic lupus erythematosus [39], rheumatoid arthritis [40], and psoriasis [41], and some studies support an association with SSc [42,43], which may contribute to it. Here, IL17A is linked to systemic lupus erythematosus.