We also found statistically significant differences in the number of drusen when comparing the FH- ApoE ɛ4- HBP+ group (17.80 ± 15.00) with: (i) FH+ ApoE ɛ4- HBP- group (12.24 ± 27.49) (p-value 0.040); and (ii) FH+ ApoE ɛ4+ HBP+ group (2.67 ± 1.37) (p-value 0.016) (Table 6 and Table 7). Here, APOE is linked to familial hyperaldosteronism.