F10 and atrial fibrillation: The lower risk of mortality in patients with paroxysmal AF was reported in the post hoc analysis of the ENGAGE AF-TIMI 48 Trial (Effective Anticoagulation with Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48), which showed a lower risk of mortality in paroxysmal versus permanent AF (1.49%/year and 1.95%/year, respectively) [15].