In the present study, we investigated the association between CAD susceptibility and six VEGF polymorphisms—two in the promoter region (−1154G>A [rs1570360] and −1498T>C [rs833061]) and four in the 3′-UTR (+936C>T [rs3025039], +1451C>T [rs3025040], +1612G>A [rs10434], and +1725G>A [rs3025053]). This evidence concerns the gene VEGFA and coronary artery disorder.