Among the haplotypes of five SNPs, −1154A allele, +936T allele were associated with a decreased prevalence of CAD (A-T-C-C-G of VEGF −1154G>A/−1498T>C/+936C>T/+1451C>T/+1725G>A, AOR = 0.036, p < 0.0001; T-T-C-G-G of VEGF −1498T>C/+936C>T/+1451C>T/+1612G/A+1725G>A, AOR = 0.039, p = 0.001). This evidence concerns the gene VEGFA and coronary artery disorder.