Dai et al. showed similar results indicating an association between the expression of SNHG15 and tumor size, TNM stage and poor differentiation of HCC [30], while Chen et al. also confirmed that SNHG15 up-regulation affects tumor stage, TNM, differentiation of HCC, vascular invasion, invasive depth (T1–2 vs. T3–4) and five-year survival [32]. The gene discussed is SNHG15; the disease is hepatocellular carcinoma.