Furthermore, we found that the distributions of allelic and genotype frequencies of SNPs rs9934438, rs9923231 in the VKORC1 gene, rs5918 in the ITGB3 gene and rs2070959 in the UGT1A6 gene were significantly different between HF patient groups with and without complications (Table 5). Here, ITGB3 is linked to hydrops fetalis.