CD274 and neoplasm: PD-L1 diffuse immune expression (≥50% of neoplastic cells) was seen in a minority of clearRCC (7%), a low level of PD-L1 expression (≥1%–<50% of cells) was observed in 33% of cases and absence of expression (<1%) in 60% of cases, after in toto 3D tumor inclusion (Figure 5 and Figure 6).