In a case-control study, a group of circulating inflammatory markers were identified as possible contributors to PCa pathophysiology, including chemokine (C-X3-C motif) ligand 1 (CX3CL1), interleukin-10 (IL-10), platelet-derived growth factor-BB (PDGF-BB) (inverse associations), Chemokine (C-C motif) ligand 21 (CCL21), and Chemokine (C-C motif) ligand 11 (CCL11) (positive associations) [154]. Here, CCL21 is linked to posterior cortical atrophy.