Other modalities such as laboratory examination are recommended in the case of symptoms or risk factors characteristic for Lyme diseases or HIV and may involve complete blood count, erythrocyte sedimentation rate tests, C-reactive protein tests, rheumatoid factor tests, antinuclear antibody tests, antineutrophil cytoplasmic antibody tests, antiphospholipid antibody tests, angiotensin-converting enzyme tests, HIV testing, Lyme serology, and cerebrospinal fluid (CSF) analysis [6]. Here, ACE is linked to Lyme disease.