We examined the correlations between adiponectin plasma levels and plasma levels of selected cytokines (IL-1β, IL-2, IL-4, IL-6, IL-7, IL-8, IL-10, IL-12 p40, IL-17, G-CSF, GM-CSF, IFN-γ, MCP-1, MIP-1β, TNF-α) in patients with OA and RA. This evidence concerns the gene TNF and rheumatoid arthritis.