Figure 7 presents the relative expression of IL-6 in HFLS cultures after 24 and 72 h of stimulation with adiponectin. The cells were stimulated with adiponectin in concentrations of 250 ng/mL or 1000 ng/mL alone or together with LPS. The HFLSs were stimulated with LPS to investigate how adiponectin affects IL-6 expression in the inflammatory environment present in RA. The gene discussed is ADIPOQ; the disease is rheumatoid arthritis.