Markers such as vascular endothelial growth factor A (VEGF-A), granulocyte colony-stimulating factor (G-CSF), chemokine (C-X-C motif) ligand 1 (CXCL1), β- catenin, proliferating cell nuclear antigen (PCNA), a marker of proliferation Ki-67, caspase 3 and epidermal growth factor (EGF) are found in the literature as well as are present in our collected data, and they are important as representative of tumor progression. This evidence concerns the gene MKI67 and neoplasm.