In non-small-cell lung carcinoma (NSCLC) and osteosarcoma cells, the central role for miR-124-3p in carcinoma cell invasion and metastasis has been established [61], while miR-135a enhances metastasis formation in breast cancer by targeting homeobox A10 (HOXA10) protein [62]. The gene discussed is HOXA10; the disease is breast cancer.