ITGA2 and type 2 diabetes mellitus: For example, the positive correlation between upregulated phosphorylated integrin ITGA2 and glucose AUC, FPG, and HbA1c may suggest that the progressively increased phosphorylation of ITGA2 plays a role in (or is a consequence of) the deterioration of glycemic control as subjects progress from NGT to PDM to T2DM.