The nucleotide-binding oligomerization domain (NOD)-like pyrin domain-containing protein 3 (NLRP3) inflammasome, which consists of NLRP3, adaptor apoptosis-associated speck-like protein (ASC), and pro-caspase-1 is deemed as a vital driving factor of various liver diseases and chemical/toxin-induced liver injury [8]. This evidence concerns the gene NLRP3 and liver disorder.