NPPB and hydrops fetalis: Additionally, according to the 2017 ACC/AHA/HFSA guidelines for the use of biomarkers in the management of HF, measurement of BNP or NT-proBNP was recommended to diagnose HF class I according to the New York Heart Association (NYHA) functional classification, as well as at hospital admission and discharge for added risk stratification in HF class I and IIa, respectively [465].