PANX1 and breast cancer: Thereafter, the CC10, Cmax, or Cmax x10 of each drug (Table 1) was used as a benchmark concentration (BC) to set a working concentration range to be tested—namely, BC-BC/2-BC/10 for protein and mRNA quantification measurements, and BCx10-BCx5-BCx2-BC-BC/2-BC/10 for the assessment of effects on Panx1 channel activity (Table 1).