PEMF exposure down-regulated the mRNA expression levels of pro-inflammatory cytokines such as il1b, il6, and Tnfa in the liver and serum levels of IL-4 and IL-12 in LPS-induced septic shock mice, which indicates that PEMF prevented multiple organ failure by reducing inflammatory cytokine levels in the liver and serum. This evidence concerns the gene IL6 and Multiple Organ Failure.