PRRX1 and colorectal carcinoma: In the radiotherapy of CRC, miRNAs are involved in regulating the radiosensitivity of CRC cells, where miR-195 suppresses the expression of CARM1 and enhances the radiosensitivity of CRC cells; miR-124 can improve the radiosensitivity of CRC cells by blocking the expression of PRRX1 [108,109,110].